Publications on CULTEX^® Technology

Anal Bioanal Chem (2011) 401:3213-3220

„Analytical in vitro approach for studying cyto- and genotoxic effects of particulate airborne material”

Authors:
M. Aufderheide, S. Scheffler, N. Möhle, B. Halter, D. Hochrainer

Journal of Aerosol Science 42 (2011) 688-692

„In-vitro cell exposure for the assessment of nanoparticle toxicity in the lung – A dialog between aerosol science and biology”

Authors:
H-R. Paur, F. R. Cassee, J. Teeguarden, H. Fissan, S. Diabate, M. Aufderheide, W. G. Kreyling, O. Hänninen, G. Kasper, M. Riediker, B. Rothen-Rutishauser, O. Schmid

In vitro World Congress 2011, Montreal

„Pre-validation of the CULTEX® system assessing the acute inhalation toxicity of nanoparticles by direct exposure of cells via the air-liquid interface”

Authors:
S. Hoffmann, N. Möhle, M. Papritz, C. Pohl, M. Aufderheide

In vitro World Congress 2011, Montreal

„Need and Perspectives for the Implementation of Relevant In Vitro Methods in the Field of Inhalation Toxicology”

Authors:
N. Möhle, J. Rach, S. Scheffler, D.-J. Budde, M. Aufderheide

Eurotox 2011, Paris

“Importance of biomaterials testing prior to the construction of devices for in vitro techniques”

Authors:
J. Rach, M. Aufderheide

Eurotox 2011, Paris

„Prevalidation of the CULTEX® method: in vitro analysis of the acute toxicity of inhalable fine dusts and nanoparticles after direct exposure of cultivated human cells from the respiratory tract”

Authors:
C. Pohl, N. Möhle, M. Papritz, D. Steinritz, U. Mohr, S. Hoffmann, C.J. Kirkpatrick, M. Aufderheide

Eurotox 2011, Paris

„Exposure of a human bronchial epithelial cell line with cigarette mainstream smoke in the CULTEX® Radial Flow System (RFS)”

Authors:
D.-J. Budde, S. Scheffler, O. Krischenowski, M. Aufderheide

Exp. Toxicol Pathol. 2011 Sep; 63(6):593-8. Epub 2010 May 31

„Development of an in vitro exposure model for investigating the biological effects of therapeutic aerosols on human cells from the respiratory tract”

Authors:
U. Deschl, J.Vogel, M. Aufderheide

Journal of Aerosol Science 42 (2011) 668-692

„In-vitro cell exposure studies for the assesment of nanoparticle toxicity in the lung- A dialog between aerosol science and biology“

Authors:

Hanns-Rudolf Paur, Flemming R. Cassee, Justin Teeguarden, Heinz Fissan, Silvia Diabate, Michaela Aufderheide, Wolfgang G. Kreyling, Otto Hänninen, Gerhard Kasper, Michael Riediker, Barbara Rothen-Rutishauser, Otmar Schmid

Analytical and Bioanalytical Chemistry – DOI 10.1007/s00216-011-5163-4

„Analytical in vitro approach for studying cyto- and genotoxic effects of particulate airborne material“

Authors:
Michaela Aufderheide, Stefanie Scheffler, Niklas Möhle, Beat Halter & Dieter Hochrainer

For the complete publication, please click >>here<<

Fresenius Environmental Bulletin - PSP Volume 19, No. 8a 2010

"A model to evaluate biological effects from combined exposure to UVA/B radiation and toluene"

Authors:
M.G. Sacco, F. Pariselli, and D. Rembges

European Commission, Joint Research Centre, Institute for Health and Consumer Protection, 21027 Ispra (VA), Italy

Exp. Toxicol. Pathol. 61: 381-386, 2009

“Effects of toluene and benzene air mixtures on human lung cells (A549)”

Authors:
F. Pariselli, M.G. Sacco, J. Ponti, D. Rembges

ATLA 37: 89-141, 2009

In Vitro Models of Inhalation Toxicity and Disease

Authors:
K. BéruBé , M. Aufderheide, D. Breheny, R. Clothier, R. Combex, R. Duffin, B. Forbes, M. Gaca, A. Gray, I. Hall, M. Kelly, M. Lethem, M. Liebsch, L. Merolla, J-P. Morin, J. Seagrave, M.A. Swartz, T.D. Tetlay, M. Umachandran

Exp. Toxicol Pathol 60(2-3): 213–224, 2008

Statistical Analysis of In Vitro Data for Risk Assessment - Exemplified for a Case of Ames Test Data.

Authors:
Markus Roller and Michaela Aufderheide.

ATLA 36: 591–598, 2008

The Development of Novel Approaches to the Identificaton of Chemical and Protein Respiratory Allergens.

Authors:
E. Roggen, M. Aufderheide, Y. Cetin, R.J. Dearman, S. Gibbs, I. Hermanns, I. Kimber, J.F. Regal, C. Rovida, D.B. Warheit, S. Uhlig

Mutat. Res. 656(1-2): 82–87, 2008

Mutagenicity of Native Cigarette Mainstream Smoke and its Gas/Vapour Phase by Use of Different Tester Strains and Cigarettes in a Modified Ames Assay.

Authors:
Michaela Aufderheide and Helga Gressmann.

Exp. Toxicol Pathol 60(2-3): 163–180, 2008

An Efficient Approach to Study the Toxicological Effects of Complex Mixtures.

Author:
Michaela Aufderheide.

6^th World Congress on Alternatives and Animal Use in the Life Sciences, August 21–25, 2007, Tokyo, Japan

A Modified Ames Assay, a Useful Tool for Analysing the Mutagenic Activity of Native Complex Atmospheres.

Authors:
Michaela Aufderheide, Helga Gressmann and Ulrich Mohr

Exp. Toxicol Pathol 58(6): 383–392, 2007

A Modified Ames Assay Reveals the Mutagenicity of Native Cigarette Mainstream Smoke and its Gas Vapour Phase

Authors:
Michaela Aufderheide and Helga Gressmann

Inhalation Toxicology, 19:13–22, 2007

Cellular Mechanisms of Mainstream Cigarette Smoke - Induced Lung Epithelial Tight Junction Permeability Changes In Vitro

Authors:
Dorian S. Olivera
Program in Toxicology, College of Pharmacy, University of New Mexico Health Sciences Center. Albuquerque, New Mexico and Lovelace Respiratory Research, Albuquerque, New Mexico, USA

Susan E. Boggs, Chris Beenhouwer, James Aden and Cindy Knall
Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA

Experimental Lung Research, 33:1, 27–51, 2007

Responses of Differentiated Primary Human Lung Epithelial Cells to Exposure to Diesel Exhaust at an Air-Liquid Interface

Authors:
JeanClare Seagrave, Sandy Dunaway, Jacob D. McDonald and
Joe L. Mauderly
Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA

Patrick Hayden
MatTek Corp, Ashland, Massachusetts, USA

Christine Stidley
Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA

European Commission, Directorate-General, Joint Research Centre, Report EUR 22285 EN, 2006

Dynamic in-vitro Exposure of Human Derived Cells to Indoor Priority Pollutants

Authors:
F. Pariselli, M. G. Sacco, D. Rembges
European Commission, Joint Research Centre,
Institute for Health and Consumer Protection,
Physical and Chemical Exposure Unit, Ispra, Italy

WIT Transactions on Biomedicine and Health, Vol 10, 2006

Set-up of a Dynamic in-vitro Exposure Device
for the Study of Indoor Air Pollutant Effects on Human Derived Cells

Authors:
F. Pariselli, M. G. Sacco & D. Rembges
European Commission, Joint Research Centre,
Institute for Health and Consumer Protection,
Physical and Chemical Exposure Unit, Ispra, Italy

Research Center Karlsruhe, October 2005

Exposure System for Bioassays
Measurement of the Toxicity of Airborne Nanoparticles

Authors:
H.R. Paur, S. Mülhopt and Dr. Diabaté

Urban & Fischer, Exp Toxic Pathol 2005, Supplement Issued July, 2005

Experimental Assessment of the Toxicological Effects of
Inhaled Complex Mixtures on the Respiratory System –
Feasibility and Limitations

Workshop 23–25 April 2005 in Barcelona, Spain

Publications on CULTEX® Technology

Publications on CULTEX^® Technology